The Turkey Sleep Trap: Why You're Really Tired After Thanksgiving Dinner
- Elle

- Nov 25
- 6 min read

Picture this: You've just polished off your second helping of Thanksgiving dinner. The turkey was perfect, the stuffing was incredible, and you somehow found room for a slice of pumpkin pie. Now you're sprawled on the couch, barely able to keep your eyes open. Everyone around you is nodding off too. "It's the turkey," someone mumbles. "All that tryptophan..."
But here's the twist: turkey isn't actually what's making you sleepy. In fact, science shows that blaming the bird for your post-dinner drowsiness is one of the biggest myths in food folklore. The real culprits behind your Thanksgiving nap are far more interesting, and understanding them requires a journey through chemistry, digestion, and the sneaky ways your body responds to holiday feasts.
The Tryptophan Tale: Where the Myth Began
The turkey-makes-you-sleepy story centers on an amino acid called tryptophan. Amino acids are the building blocks of proteins, and tryptophan is what scientists call an "essential" amino acid, meaning your body can't make it on its own. You have to get it from food.
Here's where things get interesting. Your body uses tryptophan to create serotonin, a brain chemical that helps regulate your mood and makes you feel relaxed and happy. Then, when it gets dark outside, your body converts some of that serotonin into melatonin, the hormone that controls your sleep-wake cycle. With this chemical pathway in mind, it seems logical to assume that eating lots of turkey (which contains tryptophan) would flood your system with sleep chemicals and knock you out.
There's just one problem: turkey doesn't contain nearly enough tryptophan to have this effect.
Turkey Isn't Special (At Least Not in This Way)
If you measured the tryptophan content in turkey compared to other common foods, you'd discover something surprising. Turkey actually contains slightly less tryptophan per gram than chicken does. Both cheddar and Parmesan cheese contain significantly more. Beef, pork, fish, eggs, nuts, and even chocolate all contain comparable amounts of this amino acid.
Think about that for a second. You've probably never heard anyone say, "That grilled cheese sandwich just knocked me right out," or "I can't believe how sleepy this chicken made me." Yet these foods have just as much (or more) tryptophan as turkey. So why does turkey get all the blame?
The numbers tell an even more compelling story. When doctors prescribe tryptophan supplements to help people sleep, a typical dose is around four to five grams. Meanwhile, a standard serving of turkey contains only about 200 milligrams of tryptophan. You'd have to eat roughly 20 servings of turkey to match a single therapeutic dose. That's not a meal; that's a challenge eating competition.
The Blood-Brain Barrier Problem
Even if you did manage to eat enough turkey to consume significant amounts of tryptophan, there's another obstacle standing in your way: competition.
When you eat a protein-rich food like turkey, tryptophan doesn't travel to your brain alone. It's accompanied by numerous other amino acids, all competing for the same ride. To reach your brain, these amino acids need to cross something called the blood-brain barrier, a protective shield that controls what gets in and out of your brain. Specialized transport proteins act like shuttle buses, carrying amino acids across this barrier.
Here's the catch: tryptophan must compete with five other amino acids for access to these transporters. It's like trying to board an overcrowded subway car at rush hour. Since turkey and other proteins contain many different amino acids, and tryptophan is actually one of the least abundant among them, most of the tryptophan you eat never makes it to your brain. The other amino acids crowd it out.
Scientists have discovered that tryptophan can increase brain serotonin levels when taken in isolation on an empty stomach. But no natural food source contains tryptophan without other amino acids. When you eat turkey as part of a meal, especially one loaded with other proteins, the tryptophan simply can't compete effectively enough to make you drowsy.
The Real Culprits: Carbs and Calories
So if turkey isn't the villain in this story, what actually causes post-Thanksgiving exhaustion? The answer lies in everything else on your plate.
Traditional Thanksgiving meals are carbohydrate festivals. Mashed potatoes, sweet potatoes, stuffing, dinner rolls, cranberry sauce, and desserts like pumpkin pie all share one thing in common: they're packed with carbs. These foods rank high on something called the glycemic index, which measures how quickly foods break down into sugar during digestion.
When you eat a large amount of high-glycemic foods, your blood sugar levels spike rapidly. Your body responds by releasing insulin, a hormone that helps move sugar from your bloodstream into your cells for energy or storage. However, this dramatic spike is often followed by an equally dramatic crash, and that crash brings fatigue, reduced alertness, and an overwhelming desire to close your eyes.
There's a fascinating paradox here. While eating turkey with other proteins blocks tryptophan from reaching your brain, eating lots of carbohydrates can actually increase brain serotonin levels despite the fact that carbohydrates contain no tryptophan at all. Carbs trigger insulin release, and insulin helps clear those competing amino acids from your bloodstream. With less competition, more of the tryptophan that's already in your system can finally make it to your brain.
In other words, the dessert you eat after dinner might contribute more to your sleepiness than the turkey itself.
The Digestion Energy Drain
Beyond blood sugar crashes, there's another physiological factor at play: the sheer volume of food you consume during holiday meals.
Most people eat significantly more calories in one Thanksgiving meal than they would normally eat throughout an entire day. Processing all that food requires enormous amounts of energy. Your digestive system has to work overtime, and your body responds by redirecting blood flow away from other areas (including your brain and muscles) to your stomach and intestines to handle the workload.
This redirection of blood and energy is what scientists call the "rest and digest" response, controlled by your parasympathetic nervous system. It's the opposite of your "fight or flight" response. Your body essentially puts you into a lower-energy mode so it can focus on the crucial task of breaking down and absorbing all that food. The result? You feel tired, sluggish, and ready for a nap.
Studies have shown that stretching of the small intestine and loading the stomach with proteins and fats can both trigger sleepiness. It's not about any particular ingredient but rather the overwhelming quantity of food your digestive system must process.
Other Contributing Factors
The post-Thanksgiving slump doesn't happen in a vacuum. Several other factors compound your fatigue:
Alcohol consumption: Many people enjoy wine, beer, or cocktails with their holiday meals. Alcohol is a depressant that directly causes drowsiness. When you combine alcohol's sedating effects with large quantities of food, you're setting yourself up for serious sleepiness.
Stress and relief: The weeks leading up to Thanksgiving often involve significant stress from shopping, cleaning, cooking, hosting, and traveling. Once you finally sit down to eat, your body may experience a crash as all that built-up tension releases.
Relaxation and atmosphere: Holidays typically mean time off from work or school. You're probably more relaxed than usual, surrounded by family in a warm, comfortable environment. These conditions naturally make you feel more drowsy than you would in your normal routine.
Seasonal factors: Thanksgiving falls during late autumn when days are shorter and temperatures drop. These seasonal changes can affect your energy levels and sleep patterns, making you naturally more inclined to rest.
The Bottom Line
Turkey has been unfairly blamed for Thanksgiving drowsiness for decades, but the science tells a different story.
The real reasons you feel sleepy after holiday meals are:
Massive carbohydrate consumption causing blood sugar spikes and crashes
Eating enormous quantities of food that overwhelm your digestive system
Alcohol's sedating effects
The combined stress relief and relaxation of holiday gatherings
Seasonal factors affecting your energy levels
Tryptophan plays a minor supporting role at best, and turkey contains nothing special that would make it more sleep-inducing than dozens of other common foods. The next time someone at your Thanksgiving table blames the turkey for their tiredness, you'll know the truth: it's not the bird; it's the entire feast.
If you want to avoid the post-meal crash, the solution isn't to skip the turkey. Instead, eat smaller portions, go easy on the carbohydrates and alcohol, and pace yourself throughout the meal. Or you can do what many families do: embrace the tradition, enjoy the feast, and claim your rightful spot on the couch for a well-earned holiday nap. Just don't blame the turkey.
Sources
Columbia University Mailman School of Public Health. (2022). "Why Does Tryptophan in Turkey Make Us Sleepy?" Columbia Public Health. https://www.publichealth.columbia.edu/news/why-does-tryptophan-turkey-make-us-sleepy
Healthline. (2020). "Why Does Turkey Make You Sleepy? It Actually Doesn't." https://www.healthline.com/health/why-turkey-make-you-sleepy
Inside UNC Charlotte. (2024). "The truth about tryptophan and Thanksgiving turkey tiredness." https://inside.charlotte.edu/2024/11/22/the-truth-about-tryptophan-and-thanksgiving-turkey-tiredness/
McGill University Office for Science and Society. (2024). "Turkey Doesn't Make You Sleepy." https://www.mcgill.ca/oss/article/health-and-nutrition-did-you-know/turkey-doesnt-makes-you-sleepy
Scientific American. (2024). "Does Turkey Make You Sleepy?" https://www.scientificamerican.com/article/fact-or-fiction-does-turkey-make-you-sleepy/
Texas Health Resources. "The Turkey-Tryptophan Connection: Is It Really What's Behind the Thanksgiving Snooze?" https://www.texashealth.org/areyouawellbeing/Eating-Right/The-Turkey-Tryptophan-Connection-Is-It-Really-Whats-Behind-the-Thanksgiving-Snooze
TODAY. (2024). "Does eating turkey really make you sleepy? The truth about tryptophan." https://www.today.com/health/what-turkey-makes-you-sleepy-truth-about-tryptophan-t142417
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